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This is a selection of other recent work from the TB CAB and its members.

Webinar: Speed-Up, Scale-Up TB Testing Pt. 2: National Diagnostic Networks: Which TB Tests Go Where?
30 September 2024

The Diagnostics Equity Consortium (DEC) and the Global TB Community Advisory Board (TB CAB) hosted the second webinar of a three-part study club online series exploring the evolving TB diagnostic landscape and strategies to increase TB testing coverage.

The second session was held on 10 October 2024, and dove into how national diagnostic networks can be optimized for a greater reach. The speakers explored the placement and distribution of TB tests, given test specifications, health system requirements, and the preferences of communities.

Get full information about the webinar here.

Webinar: Speed-Up, Scale-Up TB Testing Pt. 1: Maximizing Impact of Newer and Emerging Diagnostics
12 September 2024

On 17 September, 2024, the Diagnostics Equity Consortium (DEC) and the Global TB Community Advisory Board (TB CAB) hosted a three-part study club online series exploring the evolving TB diagnostic landscape and strategies to increase TB testing coverage. This first session dove into the current TB testing gap and explore the latest testing tools and strategies that have the potential to drive change.

View the webinar recording here.

Bedaquiline: what might the future hold?
26 July 2024

Lancet Microbe. 2024 Jul 26:100909. doi: 10.1016/S2666-5247(24)00149-6.
Emily S Shaw, Neil G Stoker, Jessica L Potter, Helgard Claassen, Alasdair Leslie, Conor D Tweed, Chen-Yuan Chiang, Francesca Conradie, Hanif Esmail, Christoph Lange, Lancelot Pinto, Oxana Rucsineanu, Derek J Sloan, Grant Theron, Phumeza Tisile, Teck Chuan Voo, Robin M Warren, Limakatso Lebina, Marc Lipman.

Read the 26 July 2024 Lancet Microbe article.

Research on the treatment of rifampin-susceptible tuberculosis-Time for a new approach
25 July 2024

PLoS Med. 2024 Jul 25;21(7):e1004438. doi: 10.1371/journal.pmed.1004438.
William Burman, Oxana Rucsineanu, C Robert Horsburgh, James Johnston, Susan E Dorman, Dick Menzies

Read the 2024 July PLoS Med article

Ketho Angami’s Presentation on the 1/4/6×24 Campaign
4 July 2024

The recording during the AIDS 2024 Affiliated Independent Event: Find all people with TB and HIV, treat all of them, save lives & stop the spread of both, held on 4th of July 2024.

Available here. (00:14:00-00:26:09)

Addressing the Needs of People with Extensively Drug-Resistant TB Through Pre-Approval Access to Drugs and Research
11 December 2023

A viewpoint, published in Public Health Action, advocates for transparent, accessible pre-approval access as a core element of person-centered care for drug-resistant TB.

Multiple therapeutic options exist for people with drug-resistant TB (DR-TB), but there is an urgent need to improve access to novel compounds and regimens for people with difficult to treat forms of TB. In addition to formal research studies and clinical trials, other mechanisms of accessing promising new TB compounds need to be introduced as soon as these drugs have shown efficacy and safety in phase II trials. Pre-approval access programs for newer TB drugs such as bedaquiline, delamanid, and pretomanid all suffered from shortcomings. These can be addressed for the next generation of new TB drugs through a series of concerted actions by stakeholders at multiple levels.

Access the Public Health Action viewpoint here.

Two TB CAB Position Papers Published in Public Health Action
3 September 2023

Two position papers, developed by the Global TB Community Advisory Board (TB CAB), were published in the September 2023 issue of Public Health Action.

Public Health Action is the peer-reviewed open access journal of The International Union Against Tuberculosis and Lung Disease. It reports new knowledge across all relevant areas of operational research including: infection control, nutrition, TB, HIV, vaccines, smoking, COVID-19, microbial resistance and disease outbreaks.

The September 2023 issue of Public Health Action is available here

TB CAB 10-Year Anniversary Evaluation Report 2011–2021 and Podcast
12 July 2022

In 2021, the Global Tuberculosis Community Advisory Board (TB CAB) celebrated its tenth anniversary of advocating for community engagement in research and improved access to TB prevention, treatment, and diagnostic technologies. Since its founding in 2011, 37 members from 18 different countries have served on the TB CAB, revolutionizing a long dormant field and playing a key role in informing and accelerating research and access to new TB tools necassary to improve the lives of TB-affected communities.

To commemorate and learn from the TB CAB’s first decade, Andrea DeLuca of Research for Impact has prepared a thorough report based on several dozen interviews with current and former members, as well as key collaborators and colleagues. The report distills key findings from this qualitative research process, and points toward a path forward for the years ahead.

An accompanying 3-part podcast series, Agents of Change: How the Global TB Community Advisory Board Transformed History’s Oldest Pandemic, chronicles the history of the TB CAB from its roots in global HIV activism through its present campaign to expand access to bedaquiline for people living with drug-resistant TB. It’s narrated by Treatment Action Group (TAG) Executive Director Mark Harrington and palliative care physician Bactrin Killingo, founding members of the TB CAB whose recollections helped formulate the basis of the show.

You can listen to the podcasts, as well as download the report and the transcripts of the three-part podcast series here.
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