WHO Announces Forthcoming Updates on the Diagnosis of TB
24 September 2024
24 September 2024 | Geneva — In a rapid communication issued today, the World Health Organization (WHO) is announcing updates on the diagnosis of tuberculosis (TB), with a focus on concurrent use of tests in adults and adolescents living with HIV and in children, including in children living with HIV:
- concurrent use of molecular test on respiratory samples and LF-LAM on urine for diagnosis of TB in adults and adolescents with HIV has improved accuracy and moderate cost requirements compared with single testing;
- concurrent use of molecular test on respiratory specimens and stool for diagnosis of TB in children has improved accuracy and moderate cost requirements compared with single testing;
- concurrent use of molecular test on respiratory samples, stool, and LF-LAM on urine in children living with HIV has improved accuracy and moderate cost requirements compared with single testing;
- two new diagnostic classes have been established: low complexity automated nucleic acid amplification tests (LC-aNAATs) and low complexity manual nucleic acid amplification tests (LC-mNAATs).
WHO’s End TB Strategy calls for early diagnosis of TB and universal access to drug-susceptibility testing but the diagnostic gaps remain significant in many countries worldwide.
“The diagnostic options for people with TB and drug-resistant TB, including children and people living with HIV are increasing thanks to manufacturer engagement and research, generating new evidence. Ensuring that everyone in need can obtain a rapid and accurate diagnosis will advance efforts at preventing and finally eliminating TB,” said Dr Tereza Kasaeva, Director of WHO’s Global TB Programme.
Source: World Health Organization
