Utah Valley University: Research Team Discovers Promising New Strategy to Combat TB

3 February 2026

Utah Valley University press release

An international, multi-institutional team has discovered a powerful new class of compounds that could help combat TB. The findings were published in the European Journal of Medicinal Chemistry Reports.

The study describes the development of highly potent inhibitors that target Hip1, a protein used by Mycobacterium tuberculosis to survive inside human immune cells and tolerate antibiotic treatment. By inhibiting this protein, the researchers significantly reduced bacterial survival inside infected macrophages — without harming the host cells.

Read the full press release here.

Source: Utah Valley University